Friday, October 2, 2009

Clomid Nolvadex why are so many people buying these from a Offshore Generic Pharmacy

Many Pharmacy drugs are used today for onlabel use like to treat cancer that are of real medical use but many of the same drugs are also used by athletes nothing only to get an edge but it has become the norm. Buying from an Offshore Generic Pharmacy is normal no matter if you live in Australia, America, NZ, Japan or any other place in the world any offshore pharmacy on the internet can supply you with medication depending on if they require a prescription or not some Pharmacies will fill your order without the need for a prescription.

Alot of people are now using an Offshore Pharmacy to reduce their costs and to get better access to cheaper Generic drugs that work just as well.

Why would anyone spend years of hard work when you can build the same speed or power up in 1 years that it takes a natural sportman 5 years. An offshore pharmacy or at times called a mexican pharmacy or a canadian pharmacy offer many people the chance to save money of have access to drugs they just cant get but many people from all around the world are now using them to buy medications to help them in sport.

Generic Offshore Pharmacy

Nolvadex is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure.

The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Nolvadex. The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction in IGF-1 (individuals using anabolic steroids were not studied though) from use of Nolvadex. Thus, Dan Duchaine reported that it reduces IGF-1 and therefore reduces gains. However, if this effect exists at all, it must be very minor, due to the excellent gains that many have made, and from the fact that no one has noticed any such thing from Clomid, which has the same activity profile. Clomid and Nolvadex are both pharmacy medication and you should have a RX for these and can be found for sale at many offshore pharmacy sites.how to find them just goto google and type in Offshore pharmacy.

The fact that Nolvadex will reduce water retention may result in the user agreeing that gains are less, since weight gain is less, thus reinforcing the bias.

Tamoxifen citrate has a molecular weight of 563.62, the pKa' is 8.85, the equilibrium solubility in water at 37°C is 0.5 mg/mL and in 0.02 N HCl at
37°C, it is 0.2 mg/mL. Samples of generic Nolvadex taken from 5 Offshore Pharmacy companies scanned the same.
In a steadystate,
crossover study of 10 mg NOLVADEX tablets given twice a day vs. a 20 mg NOLVADEX tablet given once daily, the 20 mg NOLVADEX tablet was
bioequivalent to the 10 mg NOLVADEX tablets.
N-desmethyl tamoxifen is the major metabolite found in patients' plasma.
4-Hydroxytamoxifen and a side chain primary alcohol derivative
Tamoxifen is a substrate of cytochrome P-450 3A, 2C9 and 2D6, and an inhibitor
of P-glycoprotein.
The drug is excreted mainly as polar conjugates, with unchanged
drug and unconjugated metabolites accounting for less than 30% of the total fecal radioactivity.
Special Populations - The effects of age, gender and race on the pharmacokinetics of tamoxifen have not been determined. liver function on the metabolism and pharmacokinetics of tamoxifen have not been determined.
The clinical significance of these in vitrostudies is unknown.
Tamoxifen reduced the plasma concentration of letrozole by 37% when these drugs were co-administered. Aminoglutethimide reduces tamoxifen and N-desmethyl tamoxifen plasma concentrations.
Clinical Studies - Adjuvant Breast Cancer
breast cancer in 1985, 1990, and again in 1995. In 1998, 10-year outcome data were reported for 36,689 women in 55 randomized trials of adjuvant
NOLVADEX using doses of 20-40 mg/day for 1-5+ years. Twenty-five percent of patients received 1 year or less of trial treatment, 52% received 2 years,
and 23% received about 5 years. Forty-eight percent of tumors were estrogen receptor (ER) positive (>10 fmol/mg), 21% were ER poor 10 fmol/l), and 31% were ER unknown. Among 29,441 patients with ER positive or unknown breast cancer, 58% were entered into trials comparing NOLVADEX to
no adjuvant therapy and 42% were entered into trials comparing NOLVADEX in combination with chemotherapy vs. the same chemotherapy alone.
was 61.4% for NOLVADEX Offshore pharmacy vs. The recurrence-free rate at 10 years was 59.7% for NOLVADEX vs. 44.5% for
control (logrank 2p < 0.00001). Among women with ER positive or unknown breast cancer and negative nodes who received about 5 years of treatment,
overall survival at 10 years was 78.9% for NOLVADEX vs. The effect of the scheduled duration of tamoxifen may be described as follows. In women with ER positive or unknown breast cancer receiving 1 year
or less, 2 years or about 5 years of NOLVADEX, the proportional reductions in mortality were 12%, 17%, and 26%, respectively (trend significant at
The corresponding reductions in breast cancer recurrence were 21%, 29% and 47% (trend significant at 2p < 0.00001).
The corresponding reduction in mortality was 6% (NS). The effects of
There was no indication that
Node Positive - Individual Studies - Two studies (Hubay and NSABP B-09) demonstrated an improved disease-free survival following radical or
modified radical mastectomy in postmenopausal women or women 50 years of age or older with surgically curable breast cancer with positive axillary
nodes when NOLVADEX was added to adjuvant cytotoxic chemotherapy. methotrexate and fluorouracil). In the NSABP B-09 study, NOLVADEX was added to melphalan [L-phenylalanine mustard (P)] and fluorouracil
(F).

Trivial name Tamoxifen
Systematic name Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
CAS number 10540-29-1 or 54965-24-1 (citrate)
ATC code L02BA01
Merck Index Number 9137
Chemical formula C26H29NO or C32H37NO8 (citrate)
Molecular weight 371.5212 g/mol (without citrate)
563.6462 g/mol (with citrate)
Elimination half-life 7 days (metabolite 12 days)
Excretion hepatic
Pregnancy category X
Legal status Prescription only (US)
Controlled substance No
Routes of administration Oral

An offshore Pharmacy is used to save money and cut down on doctors visits its also very easy to purchase medication you dont have a prescription for, This is why there are now many offshore pharmacy companies on the internet today.

No matter who you are and what you need always speak to your doctor and read information on what you are taking this can help you to be safe after all its your body and you need to keep yourself healthy if you need some more information check out this Offshore Pharmacy they are the best around and they have alot of good information on the products they stock and are ranked as a great offshore pharmacy by the 10000's of people that use a offshore pharmacy every day.

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